Pyrosequencing technology provides quantitative data in sequence context within minutes and this technology applies principles of sequencing by synthesis. PyroMark Q24 is a real-time sequencing system that is highly suitable for epigenetic research and genetic analysis including mutation detection and SNP typing. Furthermore, PyroMark Q24 enables quantification of allele representation in mixed cell populations.

Pyrosequencing technology also enables analysis of single variations in the methylation pattern of single or multiple CpG sites with high accuracy.

Applications of Pyromark Q24 Pyrosequencing System include:

  • Exploring of drug-resistance development in pathogens
  • Determining of the role of epigenetic DNA methylation in gene expression regulation
  • Elucidating genetic markers for specific phenotypes
  • Detecting polymorphisms in forensic samples of mitochondrial DNA